منابع مشابه
Likelihood of aneurysmal subarachnoid haemorrhage in patients with normal unenhanced CT, CSF xanthochromia on spectrophotometry and negative CT angiography.
BACKGROUND Patients with suspected subarachnoid haemorrhage, a normal noncontrast computed tomography (CT) and cerebrospinal fluid (CSF) evidence of haemoglobin breakdown products often undergo CT angiography (CTA). If this is normal, then invasive catheter angiography may be offered. In current clinical practice, haemoglobin breakdown products are detected by spectrophotometry rather than visi...
متن کاملShould spectrophotometry be used to identify xanthochromia in the cerebrospinal fluid of alert patients suspected of having subarachnoid hemorrhage?
BACKGROUND AND PURPOSE The absence of xanthochromia in the cerebrospinal fluid (CSF) is often used to exclude subarachnoid hemorrhage (SAH). Authorities advocate spectrophotometry to measure xanthochromia, but most North American hospitals use visual inspection. We studied the diagnostic accuracy of spectrophotometry for SAH, and its potential impact on current practice. METHODS This was a pr...
متن کاملShould Spectrophotometry Be Used to Identify Xanthochromia in the Cerebrospinal Fluid of Alert Patients Suspected of Having Subarachnoid Hemorrhage?
Background and Purpose—The absence of xanthochromia in the cerebrospinal fluid (CSF) is often used to exclude subarachnoid hemorrhage (SAH). Authorities advocate spectrophotometry to measure xanthochromia, but most North American hospitals use visual inspection. We studied the diagnostic accuracy of spectrophotometry for SAH, and its potential impact on current practice. Methods—This was a pros...
متن کاملDetection of xanthochromia in cerebrospinal fluid.
Lumbar puncture (LP) still has an important role to play in the diagnosis of subarachnoid hemorrhage. Although computed tomography (CT) scanning has replaced LP as the investigation of first choice, within 24 h of ictus 5% of cases will show no evidence of hemorrhage on CT scanning; this percentage is as high as 50% by 1 week, 30% after 2 weeks, and 0% after 3 weeks (1). By definition, xanthoch...
متن کاملFluorescence Spectrophotometry
Fluorescence and phosphorescence are photon emission processes that occur during molecular relaxation from electronic excited states. These photonic processes involve transitions between electronic and vibrational states of polyatomic fluorescent molecules (fluorophores). The Jablonski diagram (Figure 1) offers a convenient representation of the excited state structure and the relevant transiti...
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ژورنال
عنوان ژورنال: New England Journal of Medicine
سال: 2004
ISSN: 0028-4793,1533-4406
DOI: 10.1056/nejm200410143511627